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A clinical prediction rule for urinary tract infections in patients with type 2 diabetes mellitus in primary care.

Venmans, L.M.A.J., Gorter, K.J., Rutten, G.E.H.M., Schellevis, F.G., Hoepelman, A.I.M., Hak, E. A clinical prediction rule for urinary tract infections in patients with type 2 diabetes mellitus in primary care. Epidemiology and Infection: 2009, 137(2), p. 166-172.
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We aimed to develop a prediction rule for urinary tract infections (UTIs) in patients with type 2 diabetes mellitus (DM2). A 12-month prospective cohort study was conducted in patients with DM2 aged > or = 45 years to predict the occurrence of recurrent UTIs in women and lower UTIs in men. Predictors for recurrent UTI in women (n=81, 2%) and lower UTIs in men (n=93, 3%) were age, number of general practitioner (GP) visits, urinary incontinence, cerebrovascular disease or dementia. In women, renal disease was an additional predictor. The optimism [corrected] corrected area under the receiver-operating curve (AUC) was 0.79 (95% CI 0.74-0.83) for women and 0.75 (95% CI 0.70-0.80) for men. Using a cut-off score of 4, women with a lower risk assignment had a probability of 0.3% for the outcome. For a cut-off score of 6, women with a higher risk assignment had a probability of 5.8%. For men these figures were 0.8 and 7.1 for a cut-off score of 2 and 4, respectively. Simple variables can be used for the risk stratification of patients. (aut. ref.)
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